Aleve Pain Relief Naproxen Sodium Tablets are proven stronger* and longer on pain than Tylenol Each Naproxen Sodium 220 mg pain medicine has the strength to last up to 12 hours. Aleve Naproxen Sodium Pain Relief Tablets provide all day strong relief from minor arthritis backaches menstrual cramps muscular aches backache toothache headache and the common cold. The Aleve pain reliever also temporarily reduces fever. This pain medication also comes in an Easy Open Cap that is covered with a cushioned material to give you better control. Not child resistant. Pain happens. Aleve it. *Based on clinical data from the first six hours after initial dosing.